Similar to the Mac backup software Arq, just give me a list of object stores I can point to (Backblaze would be my first pick). Although, for my purposes, I think iCloud Files is going to turn into most of what I need from Dropbox fast enough that'll be where I move to.
For whatever reason, no other service does binary delta uploads like Dropbox, including Google drive. No other service takes advantage of the local network when syncing multiple PC's on the same LAN.